56 Most Popular Dog Supplements

CARING FOR YOUR DOG'S JOIN

Your dog's joints, which connect two or more bones, are mostly mobile allowing the bones to move in relationship to each other.

These joints are held together by the joint capsule which has a thin inner lining called the synovial membrane which produces the synovial fluid to lubricate the joint.

The ends of the bones are covered by a smooth layer of articular cartilage, which is composed of specialised cells called Chondroycytes that produce a large amount of extracellular matrix (ECM). ECM is composed of two major components: 60% collagen (type II) & 30% proteoglycan (aggrecan). Cartilage does not contain blood vessels. The chondrocytes (cartilage cells) are supplied by diffusion; therefore, cartilage grows and repair more slowly.

The chondrocytes are responsible for the anabolic and catabolic balance of the cartilage metabolism.

Osteoarthritis (OA) is a degenerative joint disease characterised by progressive destruction of normal articular cartilage and sub-chondral bone (Martinek, 2003). It is typically manifested by pain and lameness.

OA affects more than 20% of dogs older than one year. In a post mortom study which included some 2000 dogs, 78% of which exhibited cartilage damage (Todhunter & Johnston, 2003)

The chondrocytes play a central role in the development of Osteoarthritis (OA) because they are responsible for the anabolic and catabolic balance of the cartilage metabolism. If the balance between catabolism and anabolism is disturbed, then degenerative joint disease might develop (Gelse et al. 2003; Bello & Oesser 2006).

WHY CHOOSE SUPPLEX PROGEN

Supplex Progen contains Hydrolysed Collagen and has a different method of action to most other joint supplements.

Based on current data*, the oral administration of Hydrolysed Collagen has a beneficial effect on Osteoarthritis and can help improve & maintain joint health contributing towards preserving mobility and quality of life.

*Double-Blind, Placebo-Controlled Trial published in the American Journal of Animal and Veterinary Sciences: 2010.

SUPPLEX PROGEN KEY BENEFITS

• The Hydrolysed Collagen within Supplex Progen are rapidly absorbed.
• Several research studies have demonstrated the efficacy of Hydrolysed Collagen treatment in the management of Osteoarthritis (OA).
• Hydrolysed Collagen diminishes the degenerative process.
• Hydrolysed Collagen enters the blood stream and significantly accumulate in the cartilage and other connective tissues.
• Hydrolysed Collagen is able to slow down the progression of Osteoarthritis (OA) and break the vicious cycle of joint degeneration.
• Hydrolysed Collagen addresses the cause of the disease by stimulating joint cartilage metabolism.
• Hyaluronic Acid is an essential component of cartilage and synovial fluid.
• Vitamin C contributes to normal collagen formation for the normal function of cartilage, as well as the protection of cells from oxidative stress.
• No added fillers or bulkers.